Process optimization of efavirenz film coated tablet.

ABSTRACT

Optimization is often used in pharmacy relative to formulation & processing and one may find it in literature referring to any study of formula. Optimize means to make a perfect, effective (or) functional as possible. Process optimization is the discipline of adjusting a process so as to optimize some specified set of parameters without violating some constraint. The most common goals are minimizing cost, maximizing output, and/or efficiency. This is one of major quantitative tools in industrial decision making. In the present work process parameters at developmental stages of formulation were studied extensively and after completion of the data generated during the Process Optimization of Efavirenz tablets , some critical parameters were identified and some changes are recommended in various stages of manufacturing process and finally proved that process is capable of producing a drug of required quality with proposed process.