Beneficial health effects of rutin supplementation in patients with diabetes mellitus.

ABSTRACT

Flavonoids, dietary antioxidant compounds may offer some protection against earlystage diabetes mellitus and its associated complications. The present study aimed to evaluate the effect of rutin on overall health of patients with diabetes mellitus. The effects of rutin were tested by using it as a supplement with their regular medications. The total trial period was of 120 days conducted with a gap of 30 days each. It consisted of 30 patients aging between 40-50 years, having diabetes mellitus since last 5 years. These patients were given Rutin Tablets for 60 days. Fasting Blood Sugar (FBS), Body Mass Index (BMI), blood pressures, lipid profile, serum urea and creatinine, electrolytes, SGOT (serum glutamic oxaloacetic transaminase), SGPT (serum glutamic pyruvic transaminase) and Alkaline phosphatase (ALP) were measured at baseline and then after every 30 days. Rutin tablets were stopped for next 60 days. All of above parameters were again measured on 90th and 120th day. The results showed that rutin decreased the levels of FBS, systolic and diastolic blood pressure, HDL, Serum Urea and creatinine significantly (P<0.05), whereas significant increase (P<0.05) in TGL, HDL, VLDL were seen. Decrease in the level of SGOT, SGPT, ALP and BMI is not significant.