Hemodynamic effects of aqueous extract of Artemisia campestris in adult men.

ABSTRACT

Arterial hypertension is a worldwide health problem with multiple origins. Its management remains difficult, particularly because of the pathology dependence on human lifestyle. Several ethno pharmaceutical are used to treat hypertension. Herein we investigated, for the first time, the effect of the water-boiled extract of Artemisia campestris on Human hemodynamic system. To do so, the blood pressure parameters of two groups of adult volunteers (smokers and non-smokers) were recorded before and each 15 minutes after drinking 20 ml of the boiled extract (20g of dried leaves / 1 L of water). The diastolic pressure and heart rate significantly diminished following the treatment, in both smoker and non-smoker men. In exception to a punctual reduction at 45 minutes in non- smokers, the systolic pressure did not significantly change. The classification of subjects in accordance to their hypertension statute at each time-point of recording, showed an important reduction of the stage 2 in smoking men, following the consumption of the extract. It is concluded that the water-boiled extract of Artemisia campestris could tip over arterial hypertension, especially in smokers. It is suggested that the mechanism of such effect involves epinephrine synthesis or binding to its receptor inhibition.