The effect of advanced maternal age on pregnancy outcome in women with cervical insufficiency treated with cerclage.

ABSTRACT

Background: As a woman’s age increases, infertility also increases. Women with cervical insufficiency seek pregnancy at advanced age. Objectives: This study quantifies pregnancy outcome in women with cervical incompetence according to maternal age. Methods: A register-based study conducted between May 1, 2010 to April 30, 2011 at MCH, Qassim, KSA. During this period, 8723 deliveries and 52 cases with cervical insufficiency were identified. Patients were divided according to maternal age into group 1 less than 35 years of age or group 2 at or greater than 35 years of age. Results: Out of these 52, 38(73.1%) comprised Group1 and 14 (26.9%) comprised group 2. Patients in group 2, were older, (40 vs. 27 years, P=0.00), of high gravidity (17 vs. 4, P=0.00), had less previous history of ERCP (14.3% vs.31.6% P=0.002), were likely delivered by caesarean section (0.002) and were less likely developed PROM (P=0.047). However, both groups (G1 and G2) were similar in gestational age at delivery (36.6 vs. 36.6 weeks, P=0.95), the abortion rate, [8(21.1%) vs. 2(14.3%), P=0.58], and the rate of preterm delivery, 3(10.3%) vs. 2(16.7%) respectively (P=0.57). Conclusion: pregnancy outcome in women with cervical incompetence and advanced maternal age is not influenced by maternal age.