A study of cyto-histological correlation of breast lesions.

ABSTRACT

Aim & Objective: To study the morphological aspects of various breast lesions in patients with an apparent breast lump. To correlate the cytological findings with histopathological examination. To determine the accuracy of aspiration cytology in the diagnosis of the breast lesions. To analyse the causes of the diagnostic error and ways of overcoming them. Materials & Methods: The present study included 65 cases presenting with palpable breast lump in the outpatient department of the Shri Sayaji General Hospital Vadodara. FNA was carried out on all of them and the material studied in the Department of pathology, Medical College, Baroda, from January 2009 to September 2010. All cases were also subjected to surgical biopsy or mastectomy. Results: Out of 65 cases 21 cases were diagnosed as benign breast lesions and 44 cases were diagnosed as malignant breast lesions on cytology. On histological examination out of 21 benign lesions only one shows carcinoma while all malignant lesions were confirmed. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy was 95.2%, 100%, 100%, 95.2% and 98.4% respectively. Conclusion: In conclusion, the simplicity, rapidity, lack of morbidity, a high sensitivity, a high specificity and cost effectiveness of FNAC makes it the most valuable tool in the evaluation of the breast lesions.