Retrospective and prospective study of benign and malignant uterine corpus tumours.

ABSTRACT

Background and Objectives: Uterine tumors may be localized at the corpus, isthmus and cervix. The fallopian tubes and uterine ligaments may also undergo tumor transformation. This study was undertaken to focus on uterine corpus tumors, including benign and malignant tumors. The most common uterine corpus benign tumor is leiomyoma, a proliferation of mesenchymal origin, can be seen at any time between menarche and menopause. Endometrial in on the cancer highest rank amongst genital tract malignancies in the western world but it occupies the lowest rank in the eastern hemisphere including India. Aim:- The study was undertaken to observe prevalence of benign and malignant tumour of uterine corpus according to age and classify according to WHO. Methods: This present retroprospective study was conducted in one of the tertiary care hospital of Meerut city. This study was carried out on 539 cases of female genital tract tumor, out of which 211 cases of uterine tumour during a period of ten years. For the retrospective study all blocks and slides of uterine corpus tumor available were included where as for prospective study hysterectomy specimen of uterus with suspected tumor and biopsies of endometrial tumor were included. The chi square test is applied as test of significance. Results: In our study uterine corpus 194 (71.3%) was most common site for benign tumours in female genital tract, followed by ovary 71 (26.1%), cervix 5 (1.8%) and vagina 2 (0.7%).Where as cervix 193(72.2%) most common site for malignant tumours in female genital tract was followed by ovary 32 (11.9%), uterus 17(6.3%), vagina 16(5.9%), vulva 7(2.6%) and fallopian tubes 2 (0.7%).Most common benign tumor of uterine corpus was leiomyomas 194 cases. Whereas endometrial carcinoma 14(82.3%) most common malignant tumor of uterine corpus after that sarcoma 2(11.7%) and choriocarcinoma 1(5.85%).In age group of 31-40 years maximum cases of benign tumor of uterine corpus was observed whereas maximum cases of malignant tumor of uterine corpus was seen in age group of 51-60 years. Conclusion: The data can be used for estimation of load of the benign and malignant tumours of uterine corpus, establishment of management facilities, as well as for development of the objectives & strategy.