Effect of Momordica charantia (Bitter Melon) Leaves on Haemoglobin Concentration in Male Albino Rats.

ABSTRACT

This research work was carried out to investigate the effect of the aqueous extract of Momordica charantia on haemoglobin concentration in albino rats. The aqueous extract of Momordica charantia was prepared from the leaves of the Momordica charantia plant and given orally to the experimental animals. Haemoglobin concentration was determined after two weeks of administration. The aqueous extract was prepared and given orally at doses of 80, 100, 120 and 140 mg/kg body weight daily to the experimental animals. This study was carried out at the Department of Physiology, College of Medicine, University of Ilorin between July and August 2010. The results of the work showed that there was significant decrease in mean haemoglobin concentration in test animals in comparison with the control (p<0.05). Oral administration of aqueous extract of Momordica charantia causes a decrease in haemoglobin concentration which can lead to anaemia.