Drug Eruptions Induced by Allopurinol Associated with HLA-B*5801.
Indian J Dermatol Venereol Leprol
;
2015 Jan-Feb; 81(1): 43-45
Article
in English
| IMSEAR
| ID: sea-154971
ABSTRACT
Allopurinol, a drug commonly used for treating gout and hyperuricemia, is a frequent cause of drug eruptions. Recent investigations suggest that HLA‑B*5801 allele is a very strong marker for allopurinol‑induced cutaneous adverse drug reactions (cADRs). In this article we report two cases of allopurinol‑induced drug eruptions in patients carrying the HLA‑B*5801 allele and review the literature on the association between HLA‑B*5801 and allopurinol‑induced cADRs based on a MEDLINE and PubMed search.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Aged
/
Male
/
HLA-B Antigens
/
Allopurinol
/
MEDLINE
/
Drug Eruptions
/
PubMed
/
Middle Aged
Language:
English
Journal:
Indian J Dermatol Venereol Leprol
Year:
2015
Type:
Article
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