Effectiveness of the addition of citicoline to patching in the treatment of amblyopia around visual maturity: A randomized controlled trial.
Indian J Ophthalmol
;
2014 Feb ; 62 (2): 124-129
Article
in English
| IMSEAR
| ID: sea-155521
ABSTRACT
Aim:
To study the effectiveness of the addition of citicoline to patching in the treatment of amblyopia in the age group of 4‑13 years. Materials andMethods:
A randomized controlled trial, which included patients who were randomly divided into two groups. Both the groups received patching therapy till plateau was achieved in phase 1 of the study. Then in phase 2, group I received citicoline plus patching and group II continued to receive only patching. OutcomeMeasures:
Outcome was measured by the visual acuity in logMAR every month in phase 1 till plateau was achieved and then for 12 months in phase 2.Results:
No significant difference was found in the mean visual acuities in these two groups in phase 1 till plateau was reached. In phase 2, for the initial four months, there was no significant difference in the visual acuities in these two groups, at the respective intervals. However, five months onward, up to 12 months, there was a significant difference in the visual acuities in these groups.The result was the same in younger patients (< seven years of age) as well as in older patients (> seven years of age). In phase 2, the mean proportional improvement in group I was significantly more than that in group II, at two months and onward, at the respective intervals.Conclusion:
The improvement in visual acuity with citicoline plus patching was significantly more than that with patching alone, in one year of treatment.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Controlled clinical trial
Language:
English
Journal:
Indian J Ophthalmol
Year:
2014
Type:
Article
Similar
MEDLINE
...
LILACS
LIS