Sensitivity and specificity of nonmydriatic digital imaging in screening diabetic retinopathy in Indian eyes.
Indian J Ophthalmol
;
2014 Aug ; 62 (8): 851-856
Article
in English
| IMSEAR
| ID: sea-155725
ABSTRACT
Background:
Nonmydriatic digital imaging (NMDI) is ideal for screening diabetic retinopathy (DR), but its use in Indian eyes has not been evaluated.Aim:
The aim was to evaluate the sensitivity and specifi city of NMDI as a screening tool in detecting DR in Indian eyes.Design:
A prospective, nonrandomized, noncomparative, noninterventional study. Materials andMethods:
A total of 500 diabetic patients visiting the endocrinology clinic (September 2008-June 2010) underwent NMDI (Zeiss Procam), followed by routine dilated fundus photography (FP; Zeiss Visupac 450+) of 345° retinal fi elds (1) optic disc and macula, (2) superotemporal, and (3) nasal to optic disc. Two-masked retina specialists graded the images for quality and severity of DR, and compared between NMDI and dilated FP. StatisticalAnalysis:
SPSS Windows 17 for version.Results:
Mean age was 52.97 ± 13.46 years (306 males 194 females). The rate of ungradable images was 30.6% and 31% by the two observers. By observer 1, the sensitivity and specifi city of detecting any DR was 58.8% and 69.1%, respectively, ( = 0.608) and sight-threatening DR (STDR) was 63.1% and 68.9%, respectively, ( = 0.641). By observer 2, the sensitivity and specifi city was 57.3% and 68.3%, respectively, for any DR ( = 0.593) and 62.8% and 68.3%, respectively, for STDR ( = 0.637). The level of agreement between two observers was high ( = 0.96).Conclusion:
A high rate of poor quality photographs and low sensitivity limited the use of NMDI as a perfect screening system, particularly in dark iris population with diabetes as seen in Indian eyes.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Diagnostic study
/
Screening study
Language:
English
Journal:
Indian J Ophthalmol
Year:
2014
Type:
Article
Similar
MEDLINE
...
LILACS
LIS