Cytoplasmic-anti-neutrophil cytoplasmic antibodies targeting myeloperoxidase in Wegener's granulomatosis: A rare phenomenon.
Indian J Pathol Microbiol
;
2014 Jul-sept 57 (3): 470-472
Article
in English
| IMSEAR
| ID: sea-156090
ABSTRACT
Wegener’s granulomatosis (WG) patients can rarely have antineutrophil cytoplasmic antibodies (ANCAs) directed against myeloperoxidase (MPO), producing a cytoplasmic pattern on indirect immunofluorescence (IIF). This has important implications in the diagnosis and pathophysiology of the disease. We present to you a report of three cases of WG, demonstrating a cytoplasmic- ANCA pattern on indirect IIF, but directed against MPO. It is necessary to diagnose a patient taking into account both the autoimmune test results and the clinical features.
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Index:
IMSEAR (South-East Asia)
Language:
English
Journal:
Indian J Pathol Microbiol
Year:
2014
Type:
Article
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