Evaluation of arterial stiffness in elderly with prehypertension.
Indian J Physiol Pharmacol
;
2015 Jan-Mar ; 59 (1) : 16-22
Article
in English
| IMSEAR
| ID: sea-156238
ABSTRACT
Arterial stiffness is an independent marker of cardiovascular (CV) risk that increases with age. Hypertension is known to augment the age-related arterial stiffness. The influence of prehypertension on arterial stiffness in elderly is least studied. The present study was aimed to assess the age-associated arterial stiffness in the elderly subjects with prehypertension. A cross sectional study was conducted on elderly subjects aged 60-80 years with prehypertension (n=25) and age-matched normotensives (n=20). The arterial stiffness was assessed by measuring (1) Pulse wave velocity between carotid-femoral (c-f PWV) and brachial-ankle (baPWV) (2) Augmentation index (AIx) and (3) Arterial stiffness index (ASI) at brachial (bASI) and tibial artery (aASI). We found a significant increase in c-f PWV (p<0.001), baPWV (p<0.001) and AIx@75 (p<0.001) in prehypertensives than normotensive elderly individuals. There was no significant difference in the ASI at brachial and tibial arteries. The significant predictor of c-f PWV and AIx@75 was SBP (β=0.584, p=0.04; β=0.700, p=0.019 respectively), and aASI was PP (β=0.493, p=0.049). These findings show an augmentation of age-related arterial stiffness in elderly with prehypertension.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Language:
English
Journal:
Indian J Physiol Pharmacol
Year:
2015
Type:
Article
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