Analysis of association of TaqI VDR gene polymorphism with the chronic periodontitis in Dravidian ethnicity.
Indian J Hum Genet
;
2013 Oct-Dec ;19 (4): 465-468
Article
in English
| IMSEAR
| ID: sea-156615
ABSTRACT
AIM:
The aim of this study is to analyze the association of TaqI vitamin D receptor (VDR) gene polymorphism with the chronic periodontitis (CP) in Dravidian ethnicity. MATERIALS ANDMETHODS:
A total of 120 subjects were recruited for this study, which included 60 CP and 60 healthy controls. TaqI VDR gene polymorphism was analyzed using specific primers and amplified by polymerase chain reaction (PCR) and visualized under 2% agarose gel.RESULTS:
Our study results showed that Tt and tt genotype had a higher frequency of occurrence in CP compared with controls. Similarly, t allele was found to be associated with CP.CONCLUSION:
Our study concludes that TaqI VDR gene polymorphism is associated with CP in Dravidian ethnicity.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Polymorphism, Genetic
/
Female
/
Humans
/
Male
/
Ethnicity
/
Receptors, Calcitriol
/
Adult
/
Taq Polymerase
/
Alleles
/
Chronic Periodontitis
Country/Region as subject:
Asia
Language:
English
Journal:
Indian J Hum Genet
Year:
2013
Type:
Article
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