Cord Blood Hematological Profile of Sudanese Neonates at Birth in Khartoum State.

ABSTRACT

Background and Objectives: Hematology of newborn recently represented as area of study focusing in study of umbilical cord blood and its elements in general. Identification of expected normal hematological values essentially requires as baseline data to facilitate detection of any congenital or acquired disorders present at time of birth. We aim to estimate hematological parameters and hemoglobin electrophoresis of umbilical cord blood of Sudanese neonates at birth. Methods: Study was conducted from July 2011 to June 2013 in Khartoum state maternity hospitals, five hundred healthy full term neonates of 36 - 42 weeks gestation, with weight of 2.5 kg and born to normal uncomplicated pregnant women were enrolled, 5 ml K2EDTA cord blood samples were collected to estimate CBC and hemoglobin electrophoresis. Results: the study revealed; Hb 14.35±1.55gm/dl, haematocrit 0.44.1 L/L ±5.14, MCV, MCH, and MCHC were 105.5 fl ±5.14, 33.5pg±1.99 and 33.1 gm/dl ±1.19 respectively. Cord blood mean Hb F was 61.9 %± 8.56, Hb A 37.18%±0.25, and Hb A2 0.14 %± 0.10, respectively. RBC count 4.43x1012/L ± 0.6, nRBCs count 2.3/100 WBCs ± 1.46, and absolute nRBCs count was 267.8x1012/L ± 50, white blood cells count 12.3x109/L ± 4.17 and platelet count 261 x109/L ± 83.16. Conclusion: we concluded that hemoglobin red cell indices mean values of healthy Sudanese cord blood at birth with normal reference ranges, but slightly lower than reported previous studies because of ethnological and life style differences. Fetal Hemoglobin, nRBCs, leukocyte, and platelet counts as described in other population and compatible with normal cord blood reference values.