Clinical and microbiological characteristics of Rhodotorula mucilaginosa infections in a tertiary-Care facility.
Indian J Med Microbiol
;
2014 Jul-Sept ; 32 (3): 304-309
Article
in English
| IMSEAR
| ID: sea-156924
ABSTRACT
Background:
Rhodotorula spp. are an emergent opportunistic pathogen, particularly in immunocompromised individuals. Materials andMethods:
The aim of the study was to review reported cases of Rhodotorula infection over a period of 9 years to determine epidemiology, risk factors, treatment and outcome.Results:
The Rhodotorula spp. were isolated from cerebrospinal fluid (9) and blood (5). The most common pre-disposing factors were prolonged hospital stay (>1 month) and prolonged usage of broad-spectrum antibiotics (>1 month). All the isolates were identified as R. mucilaginosa by conventional methods. Amphotericin B demonstrated lowest minimum inhibitory concentration (MIC) as compared with other anti-fungal agents (fluconazole, itraconazole and voriconazole).Conclusions:
The recognition of unusual yeasts as an agent of life-threatening infection and their intrinsic resistance increases the burden on the mycology laboratory for complete species identification and to determine minimum inhibitory concentration.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Prognostic study
/
Risk factors
Language:
English
Journal:
Indian J Med Microbiol
Journal subject:
Microbiology
Year:
2014
Type:
Article
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