Biofilm as a virulence marker in Candida species in Nosocomial blood stream infection and its correlation with antifungal resistance.
Indian J Med Microbiol
;
2015 Feb ; 33 (5_Suppl):s112-114
Article
in English
| IMSEAR
| ID: sea-157055
ABSTRACT
Nosocomial blood stream infections (BSI) due to fungi especially Candida is increasing steadily. A two year prospective study was conducted in the S.C.B. Medical College with an aim to evaluate the species distribution, antifungal susceptibility and biofi lm formation of Candida spp. isolated from nosocomial BSIs. 34 Candida spp. were isolated from 359 blood cultures. Antifungal susceptibility was performed by microbroth dilution technique and both visual and spectrophotometric method were used for biofi lm detection. C. tropicalis was the common spp. isolated followed by C. parapsilosis and others. Most (92%) of the isolates were susceptible to Amphoterecin-B and highest resistance was observed against Flucytosine (37%) and Fluconazole(35%). Biofi lm production and antifungal resistance was observed more in nonalbicans Candida spp.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Observational study
Language:
English
Journal:
Indian J Med Microbiol
Journal subject:
Microbiology
Year:
2015
Type:
Article
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