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Synthesis, Characterization and evaluation of Anti-inflammatory and Analgesic activity of Benzothiazole derivatives.
Article in English | IMSEAR | ID: sea-157324
ABSTRACT
A parent benzothiazole nucleus was synthesized by para amino acetanilide, then it is subjected to treatment with various substituted aromatic aldehydes to get the corresponding Schiff’s bases followed by treatment with pthalic anhydride to form 2-(6- acetamidobenzo[d]thiazol-2-ylcarbamoyl)benzoic acid. The structures of synthesized compounds were confirmed by various spectroscopic methods such as IR, 1H NMR and mass spectroscopy. The products were evaluated for their anti-inflammatory and analgesic activities. Some of the compounds exhibited potent activities when compared with the standards.

Full text: Available Index: IMSEAR (South-East Asia) Type of study: Practice guideline Language: English Year: 2014 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Type of study: Practice guideline Language: English Year: 2014 Type: Article