The newborn with seizures -- a follow-up study.
Indian Pediatr
;
2008 Sep; 45(9): 749-52
Article
in English
| IMSEAR
| ID: sea-15749
ABSTRACT
OBJECTIVE:
To determine the sequelae of neonatal seizures in a cohort of newborns, recruited over a six month period.DESIGN:
Prospective hospital based study.SETTING:
The neonatal intensive care unit (NICU) of a tertiary care hospital.PARTICIPANTS:
135 babies were recruited of whom 10 died and 25 were lost to follow up.METHODS:
The cases were followed up over four months.RESULTS:
68% of the babies followed up were normal; 32% had an abnormal neurological outcome. Seven (7%) developed post-neonatal epilepsy. Hypocalcemia was significantly associated with mortality (OR 21.9; 95% CI 1.2-391.2). No risk factors could be identified for post neonatal epilepsy. Presence of spike waves in the EEG was significantly related to abnormal neurological outcome (OR 3.5; 95% C.I. 1.2-10.8).CONCLUSIONS:
Majority of neonates with seizures have a normal outcome with no developmental delay or neurological deficit. Predominantly spike waves in the EEG is predictive of abnormal neurological outcome.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Prognosis
/
Seizures
/
Humans
/
Infant, Newborn
/
Developmental Disabilities
/
Prospective Studies
/
Risk Factors
/
Epilepsy
/
India
/
Nervous System Diseases
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Country/Region as subject:
Asia
Language:
English
Journal:
Indian Pediatr
Year:
2008
Type:
Article
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