Phytochemical analysis and oral hypoglycemic activity of leaf extract of leaves of andrographis stenophylla C.B. Clarke (acanthaceae).

ABSTRACT

Andrographis stenophylla C.B. Cclarke (Acanthaceae) leaves are commonly used as folk medicine in south India. The present study is planned to determine the oral hypoglycemic activity of dichloroethane (DCE) extract of Andrographis stenophylla leaves. The Andrographis stenophylla leaves showed high yield extract values in DCE, DCM (dichloromethane) and carbinol. The DCE extract showed clear compound separation in thin layer chromatography, hence that extract was used for phytochemical analysis and pharmacological study. The DCE extract showed significant oral hypoglycemic activity in rats. The present study concludes, the DCE extract of Andrographis stenophylla leaves are suitable for isolate the terpene and it’s showed significant oral hypoglycaemic activity.