Phenobarbitone prophylaxis for neonatal jaundice in babies with birth weight 1000-1499 grams.
Indian Pediatr
;
2002 Oct; 39(10): 945-51
Article
in English
| IMSEAR
| ID: sea-15813
ABSTRACT
Management of neonatal jaundice is simple but in sick, very low birth weight babies poses additional hemodynamic insult. Role of prophylactic postnatal phenobarbitone (two different dosage regimens) was evaluated prospectively on occurrence of neonatal jaundice and the need for therapy in 150 babies with birth weight 1000-1499 grams. Phenobarbitone in the dose of 10mg/kg given within 6 hours of life followed by 5mg/kg/day till day 5 of life intravenously significantly decreased the need for exchange transfusion and duration of phototherapy in babies with birth weight of 1000-1499 grams. This dosage schedule was better than dose of 5mg/kg for 5 days in significantly reducing the duration of phototherapy
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Phenobarbital
/
Phototherapy
/
Exchange Transfusion, Whole Blood
/
Female
/
Humans
/
Male
/
Infant, Low Birth Weight
/
Infant, Newborn
/
Prospective Studies
/
Jaundice, Neonatal
Type of study:
Controlled clinical trial
/
Observational study
Language:
English
Journal:
Indian Pediatr
Year:
2002
Type:
Article
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