Combined etiology of anaphylactic cardiogenic shock: Amiodarone, epinephrine, cardioverter defibrillator, left ventricular assist devices and the Kounis syndrome.
Ann Card Anaesth
;
2015 Apr; 18(2): 261-264
Article
in English
| IMSEAR
| ID: sea-158192
ABSTRACT
Anaphylactic shock is a life‑threatening condition which needs detailed and mediculous clinical assessment and thoughtful treatment. Several causes can join forces in order to degranulate mast cells. Amiodarone which is an iodine‑containing highly lipophilic benzofuran can induce allergic reactions and anaphylactic shock in sensitized patients. Epinephrine is a life saving drug, but in sulfite allergic patients it should be given with caution due its metabisulfite preservative. Metals covering cardiac defibrillators and pacemakers can act as antigens attached to serum proteins and induce allergic reactions. In anaphylactic shock, myocardial involvement due to vasospasm‑induced coronary blood flow reduction manifesting as Kounis syndrome should be always considered. Clinically, combined treatment targeting the primary cause of anaphylaxis together with protection of cardiac tissue seems to be of paramount importance.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Epinephrine
/
Heart-Assist Devices
/
Defibrillators
/
Amiodarone
/
Anaphylaxis
/
Angina Pectoris, Variant
/
Myocardial Infarction
Type of study:
Etiology study
Language:
English
Journal:
Ann Card Anaesth
Year:
2015
Type:
Article
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