Your browser doesn't support javascript.
loading
Angiotensin II inhibits Na+/K+ATPase activity in pulmonary artery smooth muscle cells via glutathionylation and with the involvement of a 15.6 kDa inhibitor protein.
Indian J Biochem Biophys ; 2015 Apr; 52 (2): 119-124
Article in English | IMSEAR | ID: sea-158207
ABSTRACT
The role of angiotensin II in regulating Na+/K+-ATPase activity has been investigated in bovine pulmonary artery smooth muscle cells (BPASMCs). Our study reveals that angiotensin II inhibits the Na+/K+ATPase activity via glutathionylation of the pump with the involvement of an increase in NADPH oxidase-derived O2.-. Additionally, angiotensin II treatment to the cells increases the inhibitory potency of the 15.6 kDa inhibitor towards the Na+/K+ATPase activity.
Subject(s)

Full text: Available Index: IMSEAR (South-East Asia) Main subject: Oxidation-Reduction / Pulmonary Artery / Angiotensin II / Sodium-Potassium-Exchanging ATPase / Enzyme Inhibitors / Glutathione Language: English Journal: Indian J Biochem Biophys Year: 2015 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: IMSEAR (South-East Asia) Main subject: Oxidation-Reduction / Pulmonary Artery / Angiotensin II / Sodium-Potassium-Exchanging ATPase / Enzyme Inhibitors / Glutathione Language: English Journal: Indian J Biochem Biophys Year: 2015 Type: Article