Sclerotiorin is non-mutagenic and inhibits human PMNL 5-lipoxygenase and platelet aggregation.
Indian J Exp Biol
;
2015 Apr; 53(4): 228-231
Article
in English
| IMSEAR
| ID: sea-158428
ABSTRACT
Sclerotiorin, isolated from the fermented broth of Penicillium frequentans, exhibited potent inhibition against human polymorphonuclear leukocytes 5-lipoxygenase and human platelet aggregation with a half maximal value 36 µM and 250 µM, respectively. Further, the Ames test has demonstrated the sclerotiorin to be non-mutagenic.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Penicillium
/
Salmonella typhimurium
/
Benzopyrans
/
Arachidonate 5-Lipoxygenase
/
Platelet Aggregation Inhibitors
/
Mutagenicity Tests
/
Neutrophils
Language:
English
Journal:
Indian J Exp Biol
Year:
2015
Type:
Article
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