D1S80 Minisatellite - Polymorphism In Five Ethnic Populations Of Maharashtra And Kerala.

ABSTRACT

The minisatellite locus D1S80 was studied in five ethnic populations, namely, Konkanastha Brahmins and Marathas of Maharashtra; Nairs, Ezhavas and Muslims from Kerala, to compare the allele and genotype frequencies. DNA isoleted from blood samples collected from 364 unrelated healthy donors was amplified by PCR and subjected to polyaerylamide gel electrophones. A total of 20 alleles and 71 genotypes were observed from the above population groups. A bimodal pattern was observed in the allele frequency distribution representing 18 and 24 as predominant ones. The observed heterozygosity was in the range of 65% to 82%. All the five population groups conformed to Hardy- Weinberg equilibrium expectations.