Reactivity of fluorodinitrobenzene with intact human leucocytes: Examination of sites of action and the molecular entities involved in interaction.
J Biosci
;
1982 Dec; 4(4): 441-448
Article
in English
| IMSEAR
| ID: sea-160181
ABSTRACT
The epsilon amino groups of lysine and to a lesser extent amino groups on phosphotidyl ethanolamine and phosphotidyl serine situated on cell membranes of normal human leucocytes have been identified as the sites of dinitrophenylation. In situ conversion of 10,000 hydrophylic amino sites into hydrophobic sites on cell surfaces causes conformational changes in cell membranes with exposures of leukaemic cell-specific neo-antigens on tagged cell surfaces.
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Index:
IMSEAR (South-East Asia)
Language:
English
Journal:
J Biosci
Year:
1982
Type:
Article
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