Circulating immune complexes in rodent and simian malaria.
J Biosci
;
1982 Dec; 4(4): 491-498
Article
in English
| IMSEAR
| ID: sea-160189
ABSTRACT
The circulating immune complexes have been detected in the sera of albino rats infected with Plasmodium berghei and rhesus monkeys infected with P. knowlesi by (i) quantitative cryoprecipitation assay and (ii) polyethylene glycol assay. In the rodent model, the levels of circulating immune complexes increased during infection and decreased considerably in the post-infection period. In the simian system, high levels were detected during peak parasitaemia. Polyethylene glycol precipitate obtained from the sera during acute P. knowlesi infection when analysed by Immunoelectrophoresis was found to contain (i) monkey IgG, (ii) four other components of monkey plasma, (iii) two components of normal monkey erythrocytes and (iv) antigen(s) of P. knowlesi.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Language:
English
Journal:
J Biosci
Year:
1982
Type:
Article
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