Variable association of DNA polymerase with the cytoskeletal fractions of resting and dividing cells.
J Biosci
;
1985 Dec; 9 (3&4): 231-236
Article
in English
| IMSEAR
| ID: sea-160498
ABSTRACT
A DNA polymerase activity associated with the detergent insoluble cytoskeletal fraction has been identified in dividing and non-dividing rat hepatocytes and a hepatoma (the Zajdela Ascitic Hepatoma). About 35 % of the enzyme is found associated with the cytoskeletal fraction of non-dividing cells as compared to about 3–6 % of the enzyme in dividing cells even though the dividing cells contain larger amounts of the extranuclear enzyme. The properties of the enzyme are similar to those of DNA polymerase-α. It is suggested that the association of the enzyme with the cytoskeletal fraction has functional significance.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Prognostic study
Language:
English
Journal:
J Biosci
Year:
1985
Type:
Article
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