Increase in hepatic ubiquinone on administration of diethylhexyl phthalate to the rat.
J Biosci
;
1987 Mar; 11(1-4): 391-397
Article
in English
| IMSEAR
| ID: sea-160536
ABSTRACT
It is shown for the first time that the content of ubiquinone of liver increases (2·5 fold) on dietary administration of the widely-used industrial plasticizer diethylhexyl phthalate to the rat. The increase is localized almost entirely in mitochondria in which the concentration of the quinone per mg protein is 1·7 times the control. Incorporation of the radioactive precursor (acetate) reveals that the biosynthesis of ubiquinone is increased in the livers of plasticizer-administered animals. The rate of degradation is not altered.
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Index:
IMSEAR (South-East Asia)
Language:
English
Journal:
J Biosci
Year:
1987
Type:
Article
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