Mechanism of hypocholesterolemic action of glucagon.

Jaya, P; Kurup, P A

Jaya, P; Kurup, P A.

J Biosci ; 1987 Jun; 12(2): 111-114

Article in English | IMSEAR | ID: sea-160568

ABSTRACT

ABSTRACT

The mechanism of hypocholesterolemic action of glucagon was studied in rats. A single injection of glucagon resulted in decreased synthesis of hepatic cholesterol, decreased release of lipoproteins into the circulation and increased degradation of cholesterol to bile acids in the liver. Lipoprotein lipase activity of the extrahepatic tissues was not affected.

Glucagon; hypocholesterolemic effect; hepatic bile acids; lipoprotein lipase

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Full text: Available Index: IMSEAR (South-East Asia) Language: English Journal: J Biosci Year: 1987 Type: Article