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Tissue distribution and antileishmanial activity of liposomised Amphotericin-B in Balb/c mice§.
J Biosci ; 1991 Dec; 16(4): 217-221
Article in English | IMSEAR | ID: sea-160792
ABSTRACT
Antileishmanial activity and organ distribution of the antifungal drug Amphotericin-B in free and liposomised form have been studied in Balb/c mice infected with Leishmania donovani. Results indicate that Amphotericin-B in the liposomised form is significantly more active than the free form. This increase in the activity is perhaps related to the reduced drug toxicity rather than the altered drug distribution at the site of infection.

Full text: Available Index: IMSEAR (South-East Asia) Language: English Journal: J Biosci Year: 1991 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Language: English Journal: J Biosci Year: 1991 Type: Article