Efforts in diagnosing early leprosy using serological techniques.
J Biosci
;
1997 Jan; 22(1): 111-116
Article
in English
| IMSEAR
| ID: sea-161101
ABSTRACT
Skin scrapings obtained from the lesions of leprosy patients of all types showed 96% positivity to the serum antibody competition test using monoclonal antibody (ML04)to 35 kDa antigen of Mycobacterium leprae. Further, in vitro culture of full thickness skin biopsies from lepromatous patients were noted to release IgG antibodies to M. leprae with a peak antibody response at 48 h. The significance of this local antibody response to Μ. leprae in skin has been discussed for its possible use in diagnosing early leprosy.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Diagnostic study
Language:
English
Journal:
J Biosci
Year:
1997
Type:
Article
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