Alignment and phylogenetic analysis of type II DNA topoisomerases.
J Biosci
;
1996 Sept; 21(5): 613-629
Article
in English
| IMSEAR
| ID: sea-161123
ABSTRACT
DNA topoisomerases have been evolved to solve the topological problems of DNA during replication, transcription, recombination and segregation. Discovery of several new enzymes and their characterization has necessitated this compilation. This analysis shows the distinct evolutionary relatedness of type II DNA topoisomerases. A striking feature is the absence of a contiguous stretch of about 160 amino acids in one of the subunits of prokaryotic type II enzymes, which might have important implications to their structure and function.
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Index:
IMSEAR (South-East Asia)
Language:
English
Journal:
J Biosci
Year:
1996
Type:
Article
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