Determination of multiclass pesticide residues in mangoes by liquid chromatography –tandem mass spectrometry.

ABSTRACT

The Development of an analytical method for the determination of 24 multiclass pesticides in mango at the ≤10 ng g-1 level. The method involves extraction of 10 g of homogenized mango samples (2 g of Sodium chloride- +8g of Magnesium sulfate) with 10 mL of Acetonitrile; Clean up by Dispersive solid phase extraction with a combination of primary secondary amine (PSA), graphitized carbon black (GCB) and anhydrous Magnesium sulfate and final estimation by LC-MS/MS with multiple reaction monitoring (MRM) mode. The mean recoveries were in the range 80-120%. The method quantifies over a linear dynamic range of 10-100 μg/kg. The methodology has been proven to be highly efficient and robust and thus the method is suitable for monitoring the Maximum Residue Limits (MRL) compliance of a wide range of pesticides combinations.