Synthesis, characterisation and antimicrobial screening of some AZO compounds.

ABSTRACT

In this study, a series of azo compounds were synthesized in excellent yields via the diazotization of different aromatic amines followed by coupling with 2-naphthol. These compounds were characterized by elemental analysis, IR, 1H NMR and 13C NMR spectral techniques. The synthesized compounds have been tested in vitro against a number of microorganisms in order to assess their antimicrobial properties using disk diffusion method. The minimum inhibitory concentrations (MIC) were also determined by the broath microdilution technique. Some of the products exhibited comparable activity with known standard drugs at same concentration.