Study on Association of Recent and Past Chlamydophila pneumoniae Infection with Classic Multiple Sclerosis.
Article
in English
| IMSEAR
| ID: sea-163290
ABSTRACT
Aims:
We conducted this study to determine if there is any correlation between Classical Multiple Sclerosis and Chlamydophilia pneumoniae infection by ELISA (IgM, IgG, IgA). StudyDesign:
cross sectional study Place and Duration of Study The present study was performed in the Department of Microbiology, Guilan University of Medical Sciences between April 2012 and April 2013Methodology:
Chlamydophila pneumoniae infection certified by ELISA in patients (n=46) and control (n=46) using commercial assays (anti- C. pneumoniae IgG, anti- C. pneumoniae IgM, and anti- C. pneumoniae IgA kits). Data were analyzed by using four statistical tests (Pearson chi square, Kendall's tau, and Spearman's rho).Results:
Seropositivity to anti- C. pneumoniae IgG was seen less frequently in patients versus controls (69.0% versus 81.4%; P=0.187). Seropositivity to anti- C. pneumoniae IgA was also observed less frequently in patients than in controls (7.2 % versus 11.6%; P= 0.479).However anti- C. pneumoniae IgM antibodies were seen more often in classical multiple sclerosis patients than it was in controls ( 11.9% versus 2.3%; P= 0.085).Conclusion:
We concluded that recent or past C. pneumoniae infection has no correlation in initiation or protection of CMS.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Observational study
Language:
English
Year:
2014
Type:
Article
Similar
MEDLINE
...
LILACS
LIS