Synthesis, characterization, antimicrobial activities and DNA–binding studies of some Ru (III) complexes of schiff bases.

ABSTRACT

A new ruthenium (III) Schiff base complexes of the type [RuX2 (PPh3)2(L)] (where X = Cl or Br; L = monobasic bidentate Ligand) have been synthesized. All the complexes were characterized by analytical, IR, electronic and EPR spectral studies. An octahedral geometry has been tentatively proposed to all the new complexes. Further the ligands and complexes were subjected to antimicrobial activity studies. The new complexes have been tested to find out the DNA – binding by electronic spectral studies and anti cancer effect.