Docking studies of emblica officinalis compounds with DNA polymerase.
Article
in English
| IMSEAR
| ID: sea-163883
ABSTRACT
For understanding the molecular mechanism one can also adopt in silico approach where the interactions such as Protein-protein interactions, Protein-compound interactions, DNA-compound interactions, DNA-protein interactions are commonly used. Here we focused on the fate of these interactions for some of the compounds of Emblica officinalis with normal DNA polymerase β. Efficacy of these compounds involves design/taking from the databases of these molecules that are probable to act on the bimolecular target. DNA polymerase beta protein PDB (1DK3) was used to dock with compounds like Quercetin, Myricetin and 3,7,3,4-Tetra Hydroxy Flavone. All these compounds showed best binding studies with DNA polymerase beta.
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Index:
IMSEAR (South-East Asia)
Language:
English
Year:
2012
Type:
Article
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