A Paper Test Card Provides Quantitative Measurement of Iodate to Improve Quality Control of Iodized Salt in Low-resource Settings.
Article
in English
| IMSEAR
| ID: sea-164932
ABSTRACT
Objectives:
Monitoring iodine content in iodized salt is necessary for program effectiveness. Iodometric titration is the most precise method but requires skills, facilities, and reagents. The WYD Iodine Checker® and Bioanalyt iCheck® are quantitative, but are expensive, require reagents and electrical power. Iodometric titration has been adapted onto a paper test card to quantitatively measure iodate in iodized salt in low-resource settings. A cell phone is used to evaluate test results. Researchers internally validated the test cards to demonstrate accuracy and conducted a field test to demonstrate applicability for quality control in factory settings.Methods:
For each sample, 3 drops of a 15 salt-to-water dilution were placed onto the test card and mixed for 3 minutes before taking a cell phone image. Images were analyzed against a calibration curve. Two researchers internally blindly validated the test cards against titration at a university lab in Indiana, USA. The field test was performed by a quality technician in a salt factory in Mombasa, Kenya.Results:
During internal validation, 78 of 100 samples ranging from 0-75 ppm iodate analyzed were within 20% of the titration result. In the field factory, 24 of 32 samples ranging from 19-55 ppm iodate analyzed by the technician were within 20% range of titration. The technician was trained within 30 minutes and carried out 24 analyses in 3 hours, compared with 15 titrations in 3 hours.Conclusions:
The paper test card offers a rapid field-friendly method with sufficient accuracy to use for quality control of iodized salt.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Language:
English
Year:
2015
Type:
Article
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