Tuberculosis As A Cause Of Change In Hematological Parameters In A Tertiary Care Hospital.

ABSTRACT

Abstracts Background & Aim: Hematopoietic system is another organ seriously affected by tuberculosis. The hematological changes sometimes act as useful factors providing a clue to diagnosis, assessing the prognosis, indicating the complication of underlying infection as well as therapy and response to therapy. Aim is to study the various hematological parameters in Z-N positive pulmonary tuberculosis patients. Methodology & Results: Present study was conducted on hematological parameters in pulmonary tuberculosis patients in the department of Pathology in MM institute of Medical Science and Research, Mullana, Ambala. The study was conducted for a period of one year from March 2013 to march 2014. Total numbers of 80 subjects were selected of Z-N positive and changes were compared with normal hematological parameters. The testing protocol was followed in the hospital laboratory. Result: showed decreased values of hemoglobin (Hb), red blood cell (RBC), packed cell volume (PCV), mean cell volume (MCV) and mean cell hemoglobin (MCH) while increased value observed in total leukocyte count (TLC), mean cell hemoglobin concentration (MCHC), erythrocyte sedimentation rate (ESR), and platelet count. Anemia noticed in 59% patients, including mild, moderate and severe. In peripheral blood film examination, microcytic hypochromic blood picture was most common. Conclusion: Various hematological abnormalities have been demonstrated in patients with pulmonary tuberculosis. These all parameters can be used as indicator in assessment of response to therapy.