Lipid profile of patients with diabetes mellitus: a cross sectional study.

ABSTRACT

Background: Dyslipidemia is one of the common disorders which is seen in most of the diabetes patients, which causes cardio vascular disorders. Objective: To detect the lipid abnormality in diabetic patients. Methods: The study was carried out at Medicine Department, K.J. Mehta hospital, Amargadh, Bhavnagar during period from September 2014 to August 2015. The lipid profiles and the fasting blood sugar values of 100 type-1 diabetic patients, 100 type-2 diabetic patients and 50 healthy subjects were studied after taking informed consent. Their serum samples were assessed for fasting blood glucose (FBG), total cholesterol (TC), triglycerides (TG), low density lipoprotein cholesterol (LDL) and high density lipoprotein cholesterol (HDL) by using standard biochemical methods. The data was collected by predesign, pretested proforma and analyzed using SPSS 17.0 (Trial version). Results: Maximum Number of patients (37% and 44%) were from age group of 20-29 years in type-1 DM & 50-59 years in type-2 DM respectively. 53% cases of type-1 DM and 70 % cases of type-2 DM had less than 140 mg/dl level of Fasting Blood Sugar (FBS. 49 % patients of type-1 DM and 30% of type-2 showed more than 200 mg/dl level of Post Prandial Blood Sugar (PPBS). Majority of type 2 DM patients (72%) showed high serum cholesterol level, while only 12% of the type1 DM patients showed high serum cholesterol level. 95% of type 1 DM patients showed normal (10-190 mg/dl) serum triglyceride level, while only 26% of type 2 DM subjects showed normal level. Serum LDL level was high (>160 mg/dl) in 78% of type 2 DM patients, while only 19% of type 1 DM patients showed higher value. All patients of type 2 had normal serum HDL level. Conclusions: The frequencies of the high cholesterol, high TG and high LDL levels were higher in the diabetic group, thus indicating that diabetic patients were more prone for dyslipidemia, which could cause cardiovascular disorders.