Pattern of Antimicrobial Resistance of Escherichia coli from Healthy Adults in Amassoma, South-South Nigeria.
Article
in English
| IMSEAR
| ID: sea-166890
ABSTRACT
Aim:
To investigate the antimicrobial resistance profile of faecal Escherichia coli to common antimicrobial agents in healthy adults in Amassoma, South Southern Nigeria. StudyDesign:
Cross-sectional study. Place and Duration of Study Department of Pharmaceutical Microbiology and Biotechnology, Niger Delta University, Bayelsa State, between February and June 2010.Methodology:
The stool samples collected were inoculated and screened for E. coli using standard microbiological protocols. The antimicrobial susceptibility test of the isolates was done using disc diffusion technique.Results:
A total of 110 (84.6%) E. coli isolates were obtained from all the samples comprising 38 (34.5%) from the villagers and 72 (65.5%) from the University students. The overall resistance profiles of all the isolates were ampicillin-95.5%, tetracycline- 72.7%, augmentin-70.9%, co-trimoxazole-54.5%, cefuroxime-44.5%, chloramphenicol- 39.1%, nalidixic acid-30.0%, nitrofurantoin-28.2%, ceftazidime-15.5%, ciprofloxacin- 14.5%, gentamicin-10.0% and ofloxacin-4.5%. The isolates from the villagers exhibited significantly higher resistances to some of the antibiotics than those from the students (P<0.05). The prevalence of multiple drug resistance among all the isolates was 76 (69.1%).Conclusion:
The observed high level of multiple drug resistance among the flora of healthy individuals call for measures to control the sales of antimicrobial agents in this country as a strategy toward the containment of antibiotic resistance.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Observational study
/
Risk factors
Language:
English
Year:
2014
Type:
Article
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