Facile Andgreen Solvent Approach for the Synthesis of Nitrogen Bridgehead-Fused Heterocyclic Nucleus.

ABSTRACT

Green Chemistry is defined as environmentally benign chemistry. The revolution in green chemistry provides enormous scopes for discovery and even application for new synthetic approaches. An efficient and general method has been described for the formation of imidazo[1,2-a]pyridine from 2-amino pyridine with substituted α- haloketones in the presence of water and acidic additives in efficient yields.