Antibacterial Activities And GC-MS Analysis of Phytocomponents of Ehretia Abyssinica R.BR. Ex Fresen.

ABSTRACT

The Ehretiaabyssinica, a small tree, belong to Boraginaceae family is traditionally known for its medicinal properties. The present study was therefore carried out to investigate the antibacterial activities and to unveil the Phytochemicals of the bioactive components in the leaves extract of this plant species. The antimicrobial activities of leaves extract was investigated against 7 medically important bacterial strains, namely Bacillus subtilius, MRSA, Micrococcus ,Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aurues and Klebsella pneumoniae. The antibacterial activity was determined using agar well diffusion method. The most susceptible bacteria to this extract were Pseudomonas aeruginosa, followed by Staphylococcus aurues, while the most resistant bacteria were Micrococcus. GC-MS analysis revealed that the ethanol leave extract of Ehretiaabyssinica contained mainly Octadecenamide (5.77%); Lucenin 2 (5.46%); Docosane and Nonacosane (3.75%); Cyclopropene (3.50%); Hematoporphyrin (2.68%); Tetratetracontane (2.36%); Dotriacontane (1.57); Acetic acid (1.53); Nmethylglycine (1.49%); Propyne antimicrobial (1.41%). All identified compounds are known to have antimicrobial activity.