Effect of Phyllanthus Amarus on Haloperidol Induced Catalepsy in Experimental Animal Models.
Article
in English
| IMSEAR
| ID: sea-169079
ABSTRACT
Objectives:
The aim of the study was to investigate the anticataleptic effect of Phyllanthus amarus ethanolic extract in Swiss albino mice.Methods:
The ethanolic extract of leaves of Phyllanthus amarus [PAEE] at a dose of 100mg/kg/body weight was administered orally for ten days. On tenth day, one hour later Haloperidol [1 mg/ kg IP] was administered to induce catalepsy.Results:
The results indicate that induction of catalepsy by Haloperidol in Swiss albino mice was significantly prevented by PAEE.Conclusions:
The anticataleptic activity of Phyllanthus amarus can be due to its effect on brain neurotransmitters or due to antioxidant property.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Language:
English
Year:
2015
Type:
Article
Similar
MEDLINE
...
LILACS
LIS