Effect of Electron Beam Radiations on Anxiety in Experimental Animal Models.

ABSTRACT

Objectives: The aim of the study was to test the effect of whole body electron beam radiation on anxiety statein Swiss albino mice. Methods: Mice were irradiated with three different doses (2Gy,4Gy,6Gy)of electron beam radiations.After 24hours of radiation exposure animals were taken for testing level of anxiety using elevated plus maze and light dark arena apparatus. Results: Whole body electron beam irradiation at doses of 2, 4 and 6Gy lead to significant (p<0.001) anxiogenic activity in irradiated mice. Conclusions: Electron beam radiation has the potential to cause anxiety.