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Antidepressant Activity of Phyllanthus Amarus Ethanolic Extract in Experimental Animal Model.
Article in English | IMSEAR | ID: sea-169095
ABSTRACT

Objectives:

The aim of the study was to investigate the antidepressant effect of Phyllanthus amarus ethanolic extract in Wistar albino rats.

Methods:

The ethanolic extract of leaves of Phyllanthus amarus [PAEE] at a dose of 100mg/kg/body weight was administered orally for ten days. On tenth day, after one hour, the animals were taken for forced swimming test, to assess the level of depression.

Results:

The results indicate PAEE has significant antidepressant activity

Conclusions:

The antidepressant activity of Phyllanthus amarus can be due to its effect on brain neurotransmitters or due to antioxidant property.

Full text: Available Index: IMSEAR (South-East Asia) Language: English Year: 2015 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Language: English Year: 2015 Type: Article