Thrombotic Microangiopathic Syndrome: A Novel Complication of Diabetic Ketoacidosis.
Indian Pediatr
;
2013 July; 50(7): 697-699
Article
in English
| IMSEAR
| ID: sea-169892
ABSTRACT
Thrombotic microangiopathic syndrome secondary to diabetic ketoacidosis is an under reported entity in children. We describe 2 girls who developed thrombotic thrombocytopenic purpura (TTP) and thrombocytopenia associated multi organ failure (TAMOF) in new onset diabetes. Both patients presented with classical findings of DKA and were intubated due to low GCS, admitted in PICU and managed according to DKA guidelines. Later on, both patients developed thrombocytopenia, acute kidney injury, and low hemoglobin along with evidence of microangiopathy on peripheral smear. One patient developed paraparesis while other patient had high LDH levels. The clinical diagnosis of TTP and TAMOF was made respectively. Both patients were treated with plasmapharesis and renal replacement therapy. Both gradually improved and were discharged.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Practice guideline
Language:
English
Journal:
Indian Pediatr
Year:
2013
Type:
Article
Similar
MEDLINE
...
LILACS
LIS