Axonal and Demyelinating Polyneuropathy Associated With Celiac Disease.

ABSTRACT

Background: The involvement of the peripheral nervous system in children with celiac disease is rare. Case characteristics A 15- year- old girl affected by celiac disease, who presented with an acute polyneuropathy after accidental reintroduction of gluten in her diet. Observation Neurological examination suggested asymmetric weakness of both legs distally. Anti-tissue transglutaminase antibodies were positive. Nerve conduction studies were consistent with a sensory-motor demyelinating peripheral neuropathy. Outcome: Symptoms improved spontaneously on a gluten-free diet. Message Polyneuropathy may occur as a complication of celiac disease in childhood.