An Asymptomatic Young Female with Chronic Hepatitis-B Presenting as Minimal Change Glomerulonephritis with Nephrotic Syndrome

ABSTRACT

Hepatitis B is a worldwide problem with high prevalence rate in our country. Kidney involvement is common in chronic hepatitis B patients. The usual pattern is membranous glomerulonephritis in children and Type I membranoproliferative glomerulonephritis in adults. A previously asymptomatic young female suffering from chronic hepatitis B with portal hypertension presented with nephrotic syndrome. Kidney biopsy revealed minimal change glomerulonephritis which is rarely seen in association with hepatitis B. Patient recovered following administration of oral steroids. We reconunend screening of all patients of nephrotic syndrome for chronic hepatitis B with viral markers in addition to HBsAg.