Serum IgG and IgA Levels in Polio and Non-polio Acute Flaccid Paralysis Cases in Western Uttar Pradesh, India.
Indian Pediatr
;
2015 Mar; 52(3): 220-222
Article
in English
| IMSEAR
| ID: sea-171167
ABSTRACT
Objective:
IgG and IgA immunocompetence of children with wild poliovirus poliomyelitis and non-polio acute flaccid paralysis.Methods:
932 cases of acute flaccid paralysis, reported in 2008-2009, were tested for presence of polio and non-polio enteroviruses according to the WHO standards. Serum IgA and IgG levels were determined by sandwich ELISA.Results:
Mean (SD) IgA levels [0.87 (0.62)g/L; n=28] of virologically confirmed poliomyelitis cases were lower than those of virus negative [1.21 (0.83)g/L; n=612] and non-polio Enterovirus positive [1.22 (0.79)g/L; n=240] cases of acute flaccid paralysis. No significant difference was observed in the concentration of IgG among these groups.Conclusion:
IgA plays an important role in protection against poliomyelitis.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Language:
English
Journal:
Indian Pediatr
Year:
2015
Type:
Article
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